For patients with port-wine stain (nevus flammeus), a permanent, congenital vascular birthmark caused by malformed capillaries under the skin.
A port-wine birthmark is something some people are simply born with — caused by small blood vessels under the skin that didn't form the usual way. Without treatment, they don't fade on their own and can get darker or thicker over time. The GreenLight Trial is designed for people who are ready to explore reducing or potentially removing the appearance of theirs.
Why Should I Participate in the GreenLight Trial?
- Access to a new treatment option not yet available outside of this trial
- Close monitoring and care from a team of specialist skin doctors
- Play a role in advancing treatment options for others living with this condition
- All study-related visits and procedures are provided at no cost to you
See if you are Eligible
Your birthmark measures at least 3 cm long and 2 cm wide — about the size of a postage stamp.
You don't need to have tried other treatments before to qualify. Our study team will review your information and let you know if you're a good fit. There is no cost to find out if you're eligible — just fill out a short online screener to get started.
Where is the Greenlight Trial Taking Place?
Check the map below to see if there is a trial location close to you.
University of California - Irvine
843 Health Sciences Rd.
Irvine, CA 92617
Maryland Dermatology, Laser, Skin, & Vein Institute
54 Scott Adam Road, Suite 301
Hunt Valley, MD 21030
West Dematology Research Center
9339 Genesee Ave. Suite 350B,
San Diego, CA 92121
Frequently Asked Questions
What is a clinical trial?
A clinical trial is a research study that tests whether a new treatment is a good option for people with a specific condition. Before any new treatment becomes widely available, it goes through a careful review process to learn more about how it works and who it may help.
Taking part is always your choice. You'll be fully informed about what's involved before you agree to anything, and you're free to leave the study at any time — no questions asked.
In the GreenLight Trial, you'll be seen by a team of doctors who specialize in skin conditions. They'll take care of you throughout the entire process and be available to answer any questions along the way.
Many people find that joining a clinical trial gives them access to treatment options they wouldn't otherwise have — while also playing a part in something bigger that could help others down the road.
How long will the study last?
The length of your participation will depend on which stage of the study you are enrolled in. Most participants can expect to be involved for several months, which includes your treatment visits and a few follow-up check-ins afterward. The study team will walk you through the full schedule before you commit to anything.
What is a Phase 2 study?
Clinical trials happen in stages, called phases. Phase 2 means the treatment has already been tested for basic safety in an earlier phase and researchers are now looking at how well it works in a larger group of people. It's an important step in bringing new treatments to the people who need them — and your participation helps make that possible.
I'm interested. How do I take the next step?
It's easy to get started. Click the 'See If You're Eligible' button on this page to fill out a short online screener. It only takes a few minutes and there's no obligation. If you appear to qualify, a member of the study team will reach out to walk you through what comes next. You're always free to ask questions before making any decisions.
